Help protect children from COVID-19

Encourage your patients to make COVID-19 vaccination part of their pediatric vaccination schedule to reduce the public health burden of this vaccine-preventable disease.¹

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What to know about COVID-19 & children

1.

Children in the US are undervaccinated against COVID-19.

62.4 million US children are not up to date on the recommended COVID-19 vaccination.²*

2.

Young children are at high risk for severe outcomes.

Despite this risk, only 5.8% of kids ages 6-23 months have an updated COVID vaccine.³

3.

Parents trust their child's doctor about COVID-19 vaccine advice.

71.8% of parents said they completely or mostly trust their child's doctor regarding advice about COVID-19 vaccination.⁴

~62.4m
children are not up to date on their COVID vaccines.²
71.8%
of parents said they completely or mostly trust their child's doctor regarding advice about COVID-19 vaccination.⁴

Pediatric disease burden

Episode 1: Pediatric COVID-19 Vaccination Rates
2 min 2 sec
Episode 2: Post-COVID Conditions Resulting from Pediatric COVID-19
2 min 7 sec
Episode 3: Effective Conversations with Parents About COVID-19 Vaccination 1
1 min 46 sec
Episode 4: Effective Conversations with Parents About COVID-19 Vaccination 2
1 min 57 sec
Episode 5: CDC, AAP, and ACIP Recommended COVID-19 Vaccinations
2 min
Episode 1: Pediatric COVID-19 Vaccination Rates2 min 2 secExplores pediatric COVID-19 vaccination rates, focusing on the concerns parents may have.
Episode 1: Pediatric COVID-19 Vaccination Rates
2 min 2 sec
Episode 2: Post-COVID Conditions Resulting from Pediatric COVID-19
2 min 7 sec
Episode 3: Effective Conversations with Parents About COVID-19 Vaccination 1
1 min 46 sec
Episode 4: Effective Conversations with Parents About COVID-19 Vaccination 2
1 min 57 sec
Episode 5: CDC, AAP, and ACIP Recommended COVID-19 Vaccinations
2 min

COVID-19-related hospitalizations among infants <1 year outpace that of influenza⁵

Hospitalization rate per 100,000 population

16.0
12.0
8.0
4.0
0.0
OctO
NovN
DecD
JanJ
FebF
MarM
AprA
MayM
JunJ
JulJ

Surveillance month

COVID-19
Influenza

Last updated: 08/09/2024


COVID complications in children

For children who had COVID infections, up to half experience GI issues (50.2%), with other symptoms including headaches (35.6%), cough (34.7%), and fever (25.8%).⁶

Children may suffer from severe complications due to COVID-19 infection, including pneumonia; blood clots; liver, heart, or kidney damage; long COVID; and death.⁷

Post-COVID conditions

Additional complications associated with pediatric COVID-19, which were previously rare or uncommon among this age group, now factor into the public health burden.⁸

After COVID-19 infection, children and adolescents younger than 18 years old had higher rates of:⁸

  • Acute pulmonary embolism
  • Myocarditis and cardiomyopathy
  • Venous thrombotic events
  • Acute and unspecified renal failure
  • Type 1 and Type 2 diabetes
  • Coagulation and hemorrhagic disorders
  • Cardiac dysrhythmias

Pneumonia

Blood clots

Liver damage

Heart damage

Kidney damage

Long COVID

Icons represent a selection of primary COVID-19 complications in children.

What is MIS-C?

MIS-C (Multisystem inflammatory syndrome in children) is a rare but serious delayed immune response to COVID-19.9

MIS-C generally occurs 2 to 6 weeks after COVID-19 infection and is characterized by:

  • Fever of 38.0°C (100.4°F) or greater
  • Inflammation
  • New-onset manifestations in two or more categories, such as cardiac, shock, hematologic, gastrointestinal, or dermatologic conditions.9,10

COVID-19 vaccination has been shown to decrease the incidence of MIS-C in pediatric patients.¹¹

  • In a national observational study, 88% of children hospitalized for COVID-19 were not vaccinated, and 29% of these children required ICU-level care.¹²
  • In a 2023 CDC surveillance report, almost all MIS-C patients were unvaccinated and those whose vaccine-induced immunity had likely waned.¹³

Under-vaccination in children

Despite the risks, many American children are not up to date on their COVID-19 vaccines.³

COVID-19 vaccination coverage and intent for vaccination in children

Percentage

100
50
0
6 months-4 years
6-23 months
5-17 years
5-11 years
12-17 years

Age group

Definitely or probably will not get a vaccine
Probably will get a vaccine or are unsure
Definitely will get a vaccine
Received a vaccination

Last updated: 05/11/2024


The value of a strong recommendation from a trusted source

Research on vaccine-hesitancy shows that a parent's trust in their child's pediatrician is among the most influential factors they consider when deciding whether to get their child a COVID-19 vaccine.¹⁴

By making a strong recommendation, pediatricians can motivate parents and caregivers to consider COVID-19 vaccination for their child.¹⁵

Trust in sources for vaccine information⁴

Percentage of trust

60
40
20
0
Their child's pediatrician
Other healthcare providers
Government vaccine experts
Family and friends

The CDC, AAP, and ACIP recommend the updated COVID-19 vaccination for all children without contraindications aged 6 months and older.16,17

Doing so can broaden vaccine-induced immunity and help provide protection against the currently circulating SARS-CoV-2 variants and severe COVID-19-associated illness and death.¹⁸
See the guide for HCPs
Get the patient guide

Get the guides: COVID-19 disease burden overview for pediatrics

HCP guide to pediatric disease burden

Patient guide to pediatric disease burden

HCP guide to talking points for parents


Learn more about how COVID-19 can impact your patients

COVID-19 overview

Footnotes

* Based on a 2023 US population estimate of 334,914,895 from the Census Bureau, with children under 18y making up roughly 21.7% of the estimated population (or approximately 72.68 million people). “Up to date” refers to children over 5y who received at least one dose of the updated 2023-24 COVID-19 vaccine (i.e., Those who received a vaccine after September 14, 2023). For children <5 years, up-to-date status was defined based on the current recommendations (taking into account the number of doses and brand of vaccine). Estimates of vaccination coverage are based on parental reports.

References

  1. Centers for Disease Control, “Staying Up to Date with COVID-19 Vaccines.” Updated July 3, 2024. Accessed August 12, 2024. https://www.cdc.gov/covid/vaccines/stay-up-to-date.html
  2. Centers for Disease Control, “Weekly COVID-19 Vaccination Dashboard.” Updated May 11, 2024. Accessed July 15, 2024. https://www.cdc.gov/covidvaxview/weekly-dashboard
  3. Centers for Disease Control, “Child Coverage and Parental Intent for Vaccination.” Updated March 6, 2024. Accessed April 5, 2024. https://www.cdc.gov/covidvaxview/weekly-dashboard/child-coverage-vaccination.html
  4. Szilagyi, P. et al. “Parents' Intentions and Perceptions About COVID-19 Vaccination for Their Children: Results from a National Survey,” Pediatrics, Vol. 148(4), 2021. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10116994/
  5. Centers for Disease Control, “Respiratory Virus Hospitalization Surveillance Network (RESP-NET).” Updated July 26, 2024. Accessed July 29, 2024. https://www.cdc.gov/resp-net/dashboard/
  6. Behnood, S. et al. “Persistent Symptoms are Associated with Long Term Effects of COVID-19 Among Children and Young People: Results from a Systematic Review and Meta-analysis of Controlled Studies,” PloS One, Vol. 18(12), 2023. https://ncbi.nlm.nih.gov/pmc/articles/PMC10754445/
  7. Centers for Disease Control, “Older Children and Teens Need Vaccines Too!” Updated August 14, 2024. Accessed August 12, 2024. https://www.cdc.gov/vaccines/imz-schedules/adolescent-easyread.html
  8. Kompaniyets L, et al. “Post-COVID-19 Symptoms and Conditions Among Children and Adolescents — United States, March 1, 2020-January 31, 2022.” Morbidity & Mortality Weekly Report (MMWR), Vol 71, 2022. https://www.cdc.gov/mmwr/volumes/71/wr/mm7131a3.htm
  9. National Notifiable Diseases Surveillance System, “Multisystem Inflammatory Syndrome in Children (MIS-C) Associated with SARS-CoV-2 Infection 2023 Case Definition,” Updated February 28, 2023. Accessed August 12, 2024. https://ndc.services.cdc.gov/case-definitions/multisystem-inflammatory-syndrome-in-children-mis-c-2023/
  10. Miller A. et al., “Multisystem Inflammatory Syndrome in Children During Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) Delta and Omicron Variant Circulation—United States, July 2021-January 2022,” Clinical Infectious Diseases, Vol. 75, 2022. https://academic.oup.com/cid/article/75/Supplement_2/S303/6605071
  11. Yousaf, A. et al., “Multisystem Inflammatory Syndrome in Children Among Persons Who Completed a Two-dose COVID-19 Vaccine Primary Series Compared with Those Reporting No COVID-19 Vaccination, US National MIS-C Surveillance,” The Pediatric Infectious Disease Journal, Vol. 42(12), 2023. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11262462/
  12. Zambrano, L. et al., “Characteristics and Clinical Outcomes of Vaccine-Eligible US Children Under-5 Years Hospitalized for Acute COVID-19 in a National Network,” The Pediatric Infectious Disease Journal, Vol. 43(3), 2024). https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11261536/
  13. Yousaf, A. et al., “Notes from the Field: Surveillance for Multisystem Inflammatory Syndrome in Children — United States, 2023,” Morbidity and Mortality Weekly Reports (MMWR), Vol. 73, 2024. https://www.cdc.gov/mmwr/volumes/73/wr/mm7310a2.htm
  14. Mondal, P. and A. Sinharoy, “The Influence of Pediatricians' Recommendation on Caregivers' COVID-19 Vaccine Acceptance for Children: A Nationwide Cross-Sectional Survey Study from USA,” Frontiers in Pediatrics, Vol. 11, 2023. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10203465/
  15. Centers for Disease Control, “Talking with Parents about Vaccines for Infants.” Updated April 11, 2018. Accessed July 3, 2024. https://www.cdc.gov/vaccines/hcp/conversations/talking-with-parents.html
  16. Centers for Disease Control, “Interim Clinical Considerations for Use of COVID-19 Vaccines in the United States.” Updated Jun 27, 2024. Accessed July 15, 2024. https://www.cdc.gov/vaccines/covid-19/clinical-considerations/interim-considerations-us.html
  17. American Academy of Pediatrics, “Why COVID-19 Vaccines are Important for Children.” Updated September 13, 2022. Accessed July 15, 2024. https://www.aap.org/en/pages/2019-novel-coronavirus-covid-19-infections/covid-19-vaccine-for-children/why-covid-19-vaccines-are-important-for-children/
  18. Advisory Committee on Immunization Practices, “ACIP Evidence to Recommendations for Use of Moderna COVID-19 Vaccine in Children Ages 6 Months–5 Years and Pfizer-BioNTech COVID-19 Vaccine in Children Ages 6 Months–4 Years under an Emergency Use Authorization.” Updated September 5, 2024. Accessed October 23, 2024. https://www.cdc.gov/acip/evidence-to-recommendations/covid-19-moderna-pfizer-children-vaccine-etr.html
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